I know right? Breathing is such an involuntary movement that it would take some time to get used to not having to do it. I think that it would be more practical for underwater activities where we're trained to hold our breath for longer periods of time.
The only reason why the brain tells the diaphragm to make the lungs breath is because of excess acid caused by too much CO2. If there's a 'safe' level of acid, the brain doesn't make us breath, thus making super-oxygenated blood injections practical. That's why we feel panicked when we hold our breaths for too long; we're building up too much acid and the brain doesn't like it so it sends more urgent signals to breath.
I'm pretty sure, if given oxygen in this format, we will still need a method to vent the resulting CO2 generated from the various chemical reactions within our body, although it makes me wonder if we could simply exhale slowly but continuously for 20-30 minutes straight....
We could also suspend a chemical in the lipid to absorb the CO2. Or the person could consume or have something attached to them through which blood would pass in which there would be either a process to separate the O2 from the C or simply remove the CO2 entirely and vent it away.
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