Don't make your bed!

Whatever leaves the maximum surface area directly exposed is best. More surface area that has your sweat (and dead skin aka. mite food) on it is exposed to be dried out if it is left messy. Although ideally speaking, you should flip the comforter and sheets over ie. make the bed "upside down".

I would think that, overall, the less dirt you leave in the bed, the better.

You're still going to sweat