If you eat the wrong bits and don't test or prepare them properly, yes. Wolverine has survived by eating himself, so conservation of matter is a non-factor, and there's a chance that he doesn't have any of the prions, too.
Touchwood did something like this.
They found an alien that could regenerate after being wounded.
So they caged it in a warehouse and it was a large animal like alien that was as big or bigger than the largest whale.
They would cut meat from it and fed it to people as meat.
Touchwood ended up freeing it or letting it die I forget which I watched it when it came out.
But honestly it was really wrong thing to do to some one or something even if they can regenerate the missing parts.
The pain of cutting the parts off than the pain of regrowing them.
Not to mention the mental problems it cause the person to be cut into every day.
They found an alien that could regenerate after being wounded.
So they caged it in a warehouse and it was a large animal like alien that was as big or bigger than the largest whale.
They would cut meat from it and fed it to people as meat.
Touchwood ended up freeing it or letting it die I forget which I watched it when it came out.
But honestly it was really wrong thing to do to some one or something even if they can regenerate the missing parts.
The pain of cutting the parts off than the pain of regrowing them.
Not to mention the mental problems it cause the person to be cut into every day.