I love spider-man 3

Yeah. It's actually about a spider who becomes a man. That plot is happening in the background.

After biting Peter Parker, the spider slowly transforms into a human, taking on various roles as “side characters”

It's plausible. We never saw what happened to the spider.

In one of the comics one of Parker's bullies eats it and becomes the unholy abomination known as Spiders-Man, who totally doesn't eat people isn't made of spiders and he really is a real boy stop asking questions