First generation is always better

Honestly, this is just my opinion, but it really depends what you're referring to, I agree the first generation of Yu-Gi-Oh is the best, but Pokémon (games) got better as time passed, I say the same for the Sonic games, not that the older ones aren't good. But in the case of Crash Bandicoot and Spyro the Dragon, I must say the first generation was the best. I am not familiar with many of the examples shown here, but I do see your point.

This is true, however Yu-Gi-Oh GX was a close second.

Not with MLP >.>

Oh mega man, I loved those games, I wish they continued the series on 3ds

I really think being the first generation doesn't qualify something enough to be the best, though in some cases, the first is the best.