The next "proper" mass extinction where a dominant life form goes extinct like at the end of the Cretaceous or the granddaddy of them all, the Permian Mass Extinction
You should. It shows that the Sixth Mass Extinction Event is well underway and it's looking mighty grim. At an estimated 140,000 species lost every year, this is the worst since the K-Pg you mentioned.
*dies*
https://en.m.wikipedia.org/wiki/Holocene_extinction
Besides, we've already lost *ALL* of the North American megafauna... did you even click that link?