Quick google: LV-426 is a moon in the Aliens V Predator franchise which I believe according to the wiki was originally populated with humans and is now alien territory
So.... that’s the context you need
Yeah, Weyland shows up in all the Alien movies. It’s the corporation that sponsored the missions and research and later coveted the Alien lifeform leading to the spread/death and destruction. They basically make it clear that they place absolutely no value on human life.
So.... that’s the context you need